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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FASTK All Species: 18.18
Human Site: S497 Identified Species: 66.67
UniProt: Q14296 Number Species: 6
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14296 NP_006703.1 549 61104 S497 D G R V L L G S R A L R E R H
Chimpanzee Pan troglodytes XP_528000 547 60850 S495 D G R V L L G S R A L R E R H
Rhesus Macaque Macaca mulatta XP_001103566 522 58260 S470 D G R V L L G S R A L R E R H
Dog Lupus familis XP_860611 522 58238 S470 D G Q V L L G S R A L R E R H
Cat Felis silvestris
Mouse Mus musculus Q9JIX9 511 57708 S459 D G R V L L G S R A L R E R H
Rat Rattus norvegicus Q68FN9 656 75229 K607 G S K H L L G K E A I K Q R H
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_424265 559 61082 N511 D K W H Y C Q N S D I L V G S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 93 89.9 N.A. 83.7 22.5 N.A. N.A. 21.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.4 93.6 92.1 N.A. 88.3 35.6 N.A. N.A. 35.4 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 93.3 N.A. 100 40 N.A. N.A. 6.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 66.6 N.A. N.A. 20 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 86 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 15 0 0 0 0 0 0 0 0 0 % C
% Asp: 86 0 0 0 0 0 0 0 0 15 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 15 0 0 0 72 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 15 72 0 0 0 0 86 0 0 0 0 0 0 15 0 % G
% His: 0 0 0 29 0 0 0 0 0 0 0 0 0 0 86 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 29 0 0 0 0 % I
% Lys: 0 15 15 0 0 0 0 15 0 0 0 15 0 0 0 % K
% Leu: 0 0 0 0 86 86 0 0 0 0 72 15 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 15 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 15 0 0 0 15 0 0 0 0 0 15 0 0 % Q
% Arg: 0 0 58 0 0 0 0 0 72 0 0 72 0 86 0 % R
% Ser: 0 15 0 0 0 0 0 72 15 0 0 0 0 0 15 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 72 0 0 0 0 0 0 0 0 15 0 0 % V
% Trp: 0 0 15 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 15 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _